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KMID : 0370220030470010014
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Yakhak Hoeji
2003 Volume.47 No. 1 p.14 ~ p.19
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Evaluation of the Herbal Extract Mixture for the Effects of Hair-Regrowth Compared to 30% Minoxidel; Elongation of Anagen Period on C3H Mice
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이계호/Lee KH
한선일/박길홍/권영이/Han SI/Park GH/Kwon YE
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Abstract
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The hair cycle consists of three phases, growth (anagen), involution (catagen) and quiescence (telogen) phases. In order to evaluate hair re-growth effect of herbal extracts mix ture containing the 70% ethanol extracts of Polygoni Mulitiflori Radix, Mori Cortex Radix, Gingo Biloba Folium and Pine bud, we have examined the induction of the anagen phase and elongation of the anagen period using C3H mice. MorPhological examination was done by Hattori and Ogawa’s method. Enzyme activites of γ-glutamyl transpeptidase (γ-GT) and alkaline phosphatase(ALP) was detected by Bessey-Lovry-Brock’s method. Enzyme activity as a biochemical marker of cycle was investigated in the third hair cycle period of C3H mice after depilation. 3% Milnoxldll treated group and herbal extract mixture treated group were shown 3 days earlier initiation of anagen than control group. In cycling mousse skin, γ-GT activity is pronounced during anagen and greatly diminished during telogen. Herual extract mixture has shown promising hair re-growth efect on hair follicula cycles of C3H mice.
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